I'm preparing for a quite long trip. The first aid kit was the first thing that I've completed. When I was buying that bag I thought that 5 liters will be more then enough, but it revealed that I'll need separate box for medicines... Going far away in remote areas could be complicated in some points ;-) Yes, for most cases nothing happens, but it happens exactly when you're not prepared. That's why I'm always carrying full set. It's like insurance - you're buying it hoping that you'll never need to use it.